He was drafted by the New Orleans Saints second overall in the 2006 NFL Draft.
While with the Saints, Bush was named an All-Pro in 2008 and won Super Bowl XLIV in 2010 over the Indianapolis Colts.
Bush was a consensus first-team Freshman All-American selection in 2003, and became the first Trojan since Anthony Davis in 1974 to lead the Pacific-10 Conference in kickoff returns.
Bush started only fourteen times in 39 games at USC.
However, he finished tenth in NCAA Division I-A history with 6,541 all-purpose yards, racking up 3,169 yards and 25 touchdowns on 433 carries (7.3 avg) and 1,301 yards with thirteen scores on 95 catches (13.7 avg).
In addition to the Walter Camp Award, Bush also won the Doak Walker Award, which is given to the nation's best running back.
He led the nation with an average of 222.3 all-purpose yards per game and finished fourth in the NCAA Division I-A ranks with an average of 133.85 rushing yards per game.
In 2005, Bush was a unanimous first-team All-American and winner of the Heisman Trophy.